Month: April 2021

Lowering blood pressure with antihypertensive medication protects against future cardiovascular (CV) events even in people with normal or only mildly elevated blood pressure, a large meta-analysis concludes. Results showed that each 5 mm Hg reduction in systolic blood pressure lowered the relative risk for CV events by about 10% across the full spectrum of baseline
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bardoxolone Treatment for Alport Syndrome Reata Announces FDA Accepted for Filing the NDA for Bardoxolone for the Treatment of Patients With Chronic Kidney Disease Caused by Alport Syndrome PLANO, Texas, April 26, 2021 (GLOBE NEWSWIRE) — Reata Pharmaceuticals, Inc. (Nasdaq: RETA) (“Reata,” the “Company,” or “we”), a clinical-stage biopharmaceutical company, today announced that the U.S.
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NIH National Institute of Allergy and Infectious Diseases Director Anthony Fauci addresses the daily press briefing at the White House in Washington, January 21, 2021. Jonathan Ernst | Reuters White House chief medical advisor Dr. Anthony Fauci on Friday urged Americans to make sure they receive their second dose of the Covid-19 vaccines, saying the
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Using ultra-high field magnetic resonance imaging (MRI) to map the brains of people with Down syndrome (DS), researchers from Case Western Reserve University, Cleveland Clinic, University Hospitals and other institutions detected subtle differences in the structure and function of the hippocampus–a region of the brain tied to memory and learning. Such detailed mapping, made possible
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A pair of PD-1 immunotherapies used in advanced hepatocellular carcinoma (HCC) met sharply different receptions from FDA advisers reviewing accelerated approvals that failed to show benefit in confirmatory trials. In considering the two agents for previously treated HCC, the Oncologic Drugs Advisory Committee (ODAC) on Thursday unanimously recommended that FDA maintain its accelerated approval of
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Patients with neuropsychiatric manifestations of systemic lupus erythematosus (NPSLE) seem to benefit from rituximab (Rituxan) therapy, according to data from the British Isles Lupus Assessment Group Biologics Register (BILAG-BR). Indeed, the percentage of patients with active disease, as scored by the BILAG-2004 index or SLEDAI-2K (SLE Disease Activity Index 2000), fell significantly (P < .0001) when
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Posted on October 16, 2020 by Admin “A firecracker.” “The life of the party.” “Señorita Estallita Fulla Suga.” Estelle Reiff goes by many monikers, which only makes sense for a woman who has played many roles in her long life – an accomplished dancer, teacher and mother. The beloved resident of Atria Forest Hills, a
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. People who experience particular side effects after receiving a COVID-19 vaccine, such as swollen lymph nodes, may have previously been infected with the coronavirus, according to a new study published on the medRxiv preprint server. The study hasn’t yet been peer-reviewed.
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CAMBRIDGE, Mass., April 28, 2021 /PRNewswire/ – Akebia Therapeutics, Inc. (Nasdaq: AKBA), a biopharmaceutical company with the purpose to better the lives of people impacted by kidney disease, today announced that the New England Journal of Medicine (NEJM) has published the results of the global Phase 3 clinical program of vadadustat for the treatment of anemia due to chronic kidney disease
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mobocertinib Treatment for Non-Small Cell Lung Cancer Takeda Announces U.S. FDA Grants Priority Review for New Drug Application for Mobocertinib (TAK-788) as a Treatment for EGFR Exon20 Insertion+ Metastatic Non-Small Cell Lung Cancer CAMBRIDGE, Mass. & OSAKA, Japan–(BUSINESS WIRE) April 27, 2021– Takeda Pharmaceutical Company Limited (TSE:4502/NYSE:TAK) (“Takeda”) today announced that the U.S. Food and
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In this article NCLH CCL RCL Royal Caribbean CEO Richard Fain on Thursday cheered the Centers for Disease Control and Prevention’s updated coronavirus policies for cruise ships to resume sailing from U.S. ports. “We’re really very pleased and very excited because it really does set forth a pathway that we think is achievable, practical and safe,”
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Researchers have created a new, open-access tool that allows doctors and scientists to evaluate infant brain health by assessing the concentration of various chemical markers, called metabolites, in the brain. The tool compiled data from 140 infants to determine normal ranges for these metabolites. Published in the journal NMR in Biomedicine, the study describes an
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Contents of baby’s first stool were a biomarker for early-life allergy risk in a study of 100 infants. Infants who developed IgE-mediated atopy by age 1 showed a significantly poorer environment in their meconium — the fecal matter accumulated prior to birth and typically expelled within a few days of delivery — for microbiotal development
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More than 80% of patients with axillary hyperhidrosis had clinically meaningful improvement with a novel topical anticholinergic treatment, a prospective clinical trial showed. After 48 weeks of treatment, 86% of patients randomized to either of two concentrations of topical sofpironium bromide had at least a one-point improvement on the Hyperhidrosis Disease Severity Measure-Axillary (HDSM-Ax) scale.
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The Centers for Disease Control and Prevention (CDC) is finalizing new guidelines to help clinicians diagnose and manage long COVID, or post-acute sequelae of SARS-CoV2 infection. In a daylong congressional hearing on Thursday, John Brooks, MD, a medical epidemiologist at the
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Here’s another favorite from the Senior Planet archives. Enjoy!    Hanukkah, Christmas… time to think outside the cookie jar. For the holidays, baker Norma Saulino created some brand-new treats by mixing elements from well-worn recipe cards with her own take on new favorites from the web. Gingerbread + Rugelach = Gingerugelach This idea came about while I
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. A study that warned of the perils of using face masks as a precaution against contracting Covid-19 appears slated for retraction, Retraction Watch has learned. The 2020 paper, “Facemasks in the COVID-19 era: A health hypothesis,” was written by Baruch Vainshelboim,
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A team of scientists from Estonia has recently characterized the anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody response induced by an mRNA-based coronavirus disease 2019 (COVID-19) vaccine in relation to age, sex, and side-effects. The findings reveal that although the two-dose vaccine regimen initially induces robust antibody response in all age groups, older male
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