Month: June 2021

Today, the U.S. Food and Drug Administration approved Rylaze (asparaginase erwinia chrysanthemi (recombinant)-rywn) as a component of a chemotherapy regimen to treat acute lymphoblastic leukemia and lymphoblastic lymphoma in adult and pediatric patients who are allergic to the E. coli-derived asparaginase products used most commonly for treatment. The only other FDA-approved drug for such patients
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Further details from multiple cases of myocarditis linked to the Pfizer and Moderna mRNA COVID vaccines have been described in recent papers in the medical literature. The cases appear to occur almost exclusively in males and most often in younger age
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Heart failure (HF) guidelines and practice have been quick to embrace the sodium-glucose cotransporter 2 (SGLT2) inhibitor drug class after DAPA-HF, EMPEROR-Reduced, and other trials suggested that, apparently as a class, they cut cardiovascular (CV) risk in patients with heart failure and reduced ejection fraction (HFrEF) both with and without diabetes. But how they achieve
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Former Defense Secretary Donald Rumsfeld, who engineered the post-9/11 US invasions of Afghanistan and Iraq, died Tuesday of multiple myeloma, a family spokesperson told The New York Times. Rumsfeld, 88, led the Pentagon for presidents Gerald Ford and George W. Bush and was one of most influential government leaders of the first decade of the
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Doctors say a 29-year-old woman developed sepsis ― a potentially life-threatening reaction to extreme infection ― as a direct result of fillers used in a buttocks enhancement procedure. The woman, whose case will be detailed at the European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) held online July 9-12, was admitted to the hospital
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A study published last week that quickly became another flashpoint for those arguing that COVID-19 vaccines are unsafe has earned an expression of concern. The original paper, published in the MDPI title Vaccines, claimed that: The number of cases experiencing adverse reactions has been reported to be 700 per 100,000 vaccinations. Currently, we see 16 serious side
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A study analyzing the association between a wide variety of prenatal and childhood exposures and neuropsychological development in school-age children has found that organic food intake is associated with better scores on tests of fluid intelligence (ability to solve novel reasoning problems) and working memory (ability of the brain to retain new information while it
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ZED1227, a potential therapeutic transglutaminase 2 inhibitor, reduced mucosal damage from gluten in celiac disease patients, a randomized proof-of-concept trial found. At week 6, the difference in villus height-to-crypt depth average ratio, a measurement of intestinal injury, was significant at three different dosages of ZED1227 (10 mg, 50 mg, and 100 mg) compared to placebo,
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Postoperative treatment of pancreatic cancer with nab-paclitaxel (Abraxane) and gemcitabine improved survival by more than 4 months as compared with gemcitabine alone, long-term follow-up from a randomized trial showed. Median overall survival (OS) was 41.8 months with the combination versus 37.7 months with single-agent gemcitabine. The combination led to a 7% absolute improvement in 5-year
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When “Madeline” decided that she wanted to stay in-state for residency, faculty from her medical school said her chances of matching at a program in her home state were high. A recent medical graduate from the Midwest whose name has been changed for privacy purposes, Madeline was a competitive applicant. She was in the top
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COVID-19 vaccination with Pfizer or Moderna mRNA vaccines was effective in essential workers, preventing infection and reducing the severity of breakthrough illness, a real-world study found. Adjusted vaccine effectiveness was 91% (95% CI 76-97%) for full vaccination (defined as 14 days or more after dose two) and 81% (95% CI 64-90%) for partially vaccinated workers
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Tuskegee is the one-word answer some people give as a reason they’re avoiding COVID-19 vaccines. A new ad campaign launched Wednesday with relatives of men who unwittingly became part of the infamous experiment wants to change minds. Omar Neal, 63, a
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Dr. Scott Gottlieb told CNBC on Wednesday he believes there’s enough Covid immunity protection across the U.S. population that, even as the highly transmissible delta variant circulates, the country is unlikely to experience a situation nearly as dire as previous points in the pandemic. “I don’t think it’s going to be a raging epidemic across
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Younger patients, including adolescents, are less likely to suffer severe coronavirus disease 2019 (COVID-19) symptoms. This is the case even though the risk of infection with its causative pathogen – the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – is not necessarily reduced in this age group. This has led to the supposition that stronger
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An Emirates airline Boeing 777 at Sydney’s International Airport on May 01, 2021 in Sydney, Australia. James D. Morgan | Getty Images News | Getty Images Emirates airline is preparing for a summer travel surge over the next two weekends, despite growing concern over the delta coronavirus variant responsible for more than a third of
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In this article REGN NTLA Gene-editing technology CRISPR reached a major milestone this past weekend, completing its first systemic delivery as a medicine to a human body. CRISPR, or clustered regularly interspaced short palindromic repeats, effectively cuts genomes and slices DNA to treat genetic diseases. The latest breakthrough, the result of a trial between biotech
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The Pacific Northwest in the U.S. and British Columbia, Canada are being scorched by an unprecedented heat wave this summer. This rare “heat dome” is predicted to only occur once every 1,000 years or so. States across the northwest are breaking records for heat, which is not only incredibly uncomfortable, but extremely dangerous in general
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Watching a live broadcast of Russian President Vladimir Putin’s annual televised phone-in, at the newsroom of the TASS news agency. Gavriil Grigorov | TASS | Getty Images Russian President Vladimir Putin said Wednesday that he had received the Sputnik V coronavirus vaccine, as the Kremlin struggles to convince a skeptical public about the benefits of
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GAITHERSBURG, Md., June 30, 2021 /PRNewswire/ – Novavax, Inc. (Nasdaq: NVAX), a biotechnology company developing next-generation vaccines for serious infectious diseases, today announced the publication of results from the final analysis of a pivotal Phase 3 clinical trial of its COVID-19 vaccine candidate conducted in the United Kingdom in the New England Journal of Medicine (NEJM). The final analysis confirmed an overall
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