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Home Pharmaceutical

Alnylam therapy for form of heart disease succeeds in closely watched trial

admin by admin
August 3, 2022
in Pharmaceutical



Alnylam Pharmaceuticals’ treatment for an increasingly common heart disease succeeded in a closely watched clinical trial, the company said Wednesday, clearing the path to approval and affirming the promise of a drug analysts expect to reap blockbuster sales.

Patients treated with the intravenous drug, called patisiran, did significantly better than those taking a placebo on a test of how far they could walk over the course of six minutes, meeting the study’s primary goal. The 12-month trial enrolled 360 patients with ATTR-CM, a progressive heart disease. The so-called six-minute walk test is a widely accepted metric in cardiovascular medicine, one that correlates with whether a given treatment can prevent hospitalization and death in the long term.

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