Secukinumab Provides Clinical Benefit for JIA Subtypes

Secukinumab (Cosentyx), an interleukin-17A inhibitor, is effective and reasonably well tolerated for treatment of enthesitis-related arthritis (ERA) and juvenile psoriatic arthritis (JPsA) in children and adolescents, according to a phase 3 trial presented at a late breaking abstracts session of the annual European Congress of Rheumatology. On the primary outcome of time to flare, the […]

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Secukinumab Provides Clinical Benefit for JIA Subtypes

Secukinumab (Cosentyx), an interleukin-17A inhibitor, is effective and reasonably well tolerated for treatment of enthesitis-related arthritis (ERA) and juvenile psoriatic arthritis (JPsA) in children and adolescents, according to a phase 3 trial presented at a late breaking abstracts session of the annual European Congress of Rheumatology. On the primary outcome of time to flare, the […]

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Precise manipulation of folate metabolism may pave way to broadly improve health during aging

Several different causes of aging have been discovered, but the question remains whether there are common underlying mechanisms that determine aging and lifespan. Researchers from the Max Planck Institute for Biology of Aging and the CECAD Cluster of Excellence in Aging research at the University Cologne have now come across folate metabolism in their search […]

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Precise manipulation of folate metabolism may pave way to broadly improve health during aging

Several different causes of aging have been discovered, but the question remains whether there are common underlying mechanisms that determine aging and lifespan. Researchers from the Max Planck Institute for Biology of Aging and the CECAD Cluster of Excellence in Aging research at the University Cologne have now come across folate metabolism in their search […]

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Survey Shows Oncologists Underestimate How Many Cancer Patients Use Alternative Therapies

Many cancer patients use alternative or complementary therapies in conjunction with their main course of treatment, but a new survey shows that many oncologists underestimate how many of their patients are using these types of therapies. It also appears that oncologists and patients disagree about how effective each type of alternative therapy may be. Complementary […]

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Healthy With Obesity? The Latest Study Casts Doubt

People with “metabolically healthy obesity” are actually not healthy, since they are at increased risk for several adverse cardiometabolic outcomes, compared with people without obesity and or adverse metabolic profiles, new research suggests. The latest data on this controversial subject come from an analysis of nearly 400,000 people in the U.K. Biobank. Although the data also […]

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As Teen Suicide Attempts Soar, Experts Urge More Than Screening

Teen and adolescent mental health needs are at crisis levels in the wake of COVID-19, but more screening to prevent suicides won’t help without places to refer patients who seek help in emergency departments (EDs), experts told the American Medical Association (AMA) House of Delegates on Monday. Pediatric emergency physician Samantha Rosman, MD, MPH, delegate […]

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